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Journal article | December 16, 2022

Effectiveness of seasonal malaria chemoprevention (SMC) treatments when SMC is implemented at scale

Case–control studies in 5 countries

Seasonal malaria chemoprevention (SMC) has shown high protective efficacy against clinical malaria and severe malaria in a series of clinical trials. We evaluated the effectiveness of SMC treatments against clinical malaria when delivered at scale through national malaria control programmes in 2015 and 2016.